After a difficult season, Gladbach have started to turn things around a little of late, while Dortmund have struggled to piece together consistent form due to a congested fixture list.
Hoffenheim have recently hopped into third place in the Bundesliga table, leaving Dortmund with work to do if they are to secure a definite Champions League place for the coming season.
The hosts have scored six goals in their last two games, but their home form in the German top flight still remains patchy. Gladbach have won three of their last six league games at Borussia-Park.
Dortmund have a Wednesday night clash against Monaco in the Champions League to contend with, which could well see Tuchel decide to rest some players heading into the weekend.
Dortmund have won just one of their last six Bundesliga games on the road, with it looking likely that Gladbach can at least share a piece of the spoils away from Die Schwarzgelben on Saturday.
Tuchel’s men have quality in abundance, but given their heavy fixture list and poor form away from Signal Iduna Park, Gladbach have to fancy their chances.