Gareth Southgate's men will be high on confidence after putting in a good showing against Germany in a narrow 1-0 friendly defeat last week in Dortmund.
An opening day defeat to Switzerland is the only thing that has stood between Portugal and the top of Group B, with Fernando Santos' men beginning to fire on all cylinders after a sluggish start.
Gordon Strachan is under growing pressure as Scotland boss, after back-to-back 3-0 defeats against Slovakia and England that have left his side in fifth place in Europe's World Cup Qualifying Group F, with only Malta bringing up the rear.
Vladimir Petkovic has led his Switzerland side to four consecutive victories in their World Cup qualification campaign so far, which has the nation sat above Euro 2016 winners Portugal in first place in Group B.
Netherlands find themselves in second place currently in European World Cup qualification Group A, three points off top spot, while Sweden breath down their neck in third.
Romania have only suffered defeat at home once during their opening two matches in Cluj during World Cup qualifying Group E, drawing 1-1 with Montenegro before being outclassed 3-0 by league leaders Poland. On their travels, they are unbeaten.
Group E's two bottom teams clash heads in this weekend fixture, with both aiming to lift themselves into the chase for second place with a victory.
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