Manchester City are going through a tough period and had problems to get right results in the Premier League after getting thrown out of the Champions League by Monaco. Manchester City are fourth in the table, and their qualification for the Champions League is far from certain so far, which makes the visit to Southampton crucial before facing Manchester United. Southampton are a quality team, but they have virtually nothing to play for in midtable, now that they are definitely safe.
Quite ironically, Manchester City actually find it easier to win away rather than at home. They have ten away wins already, and only tend to lose to top opponents like Chelsea, Tottenham and Everton. Southampton don't fall into that category, and the potent Manchester City attack should do the job in the southern town. The odds (1.70) might not be extraordinary, but they are actually better than expected.
In addition, one could predict a high scoring affair. Eleven goals were scored in the last three games of Manchester City, and the score went over 2.5 goals in eleven out of the last 14 Southampton games. The odds are 1.65.